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Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. Connect with us at abbott.com and on LinkedIn, Facebook, Instagram, X and YouTube. *MAESTRO = minor allele enriched sequencing through recognition oligonucleotides MAESTRO was developed by researchers at the Broad Institute of MIT and Harvard. Abbott enhanced the technology for use in the next-generation Oncodetect test. † Internal estimate for addressable patient populations based on solid tumors amenable to MRD testing. ‡ Under high-end inputs Tsvetanova B, et al. Association for Molecular Pathology 2025 Annual Meeting Abstracts. J Mol Diagn. 2025;27 Suppl:S113. Gydush G, Nguyen E, Bae JH, et al. Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth. Nat Biomed Eng. 2022;6:257–266. doi:10.1038/s41551-022-00855-9. Abbott Cancer Diagnostics. LoD and Precision Results from MRD v2 AV. Internal presentation. August 3, 2026. Kotani, D., Oki, E., Nakamura, Y. et al. Molecular residual disease and efficacy of adjuvant chemotherapy in patients with colorectal cancer. Nat Med 29, 127-134 (2023). https://doi.org/10.1038/s41591-022-02115-4 Diergaarde B, Young G, Hall DW, et al. Circulating Tumor DNA as a Marker of Recurrence Risk in Stage III Colorectal Cancer: The α-CORRECT Study. J Surg Oncol. 2025;132(1):175-186. doi:10.1002/jso.27989 Exact Sciences. Oncotype DX Breast Recurrence Score® Test Surpasses 2 Million Patients Worldwide. February 3, 2026. LoBello J, et al. Poster 2025. Exact Sciences Corporation; Madison, WI. Abbott Cancer Diagnostics. Oncodetect v2 Analytical Specificity. Internal presentation. August 25, 2026. Boukouris, A.E., Michaelidou, K., Joosse, S.A. et al. A comprehensive overview of minimal residual disease in the management of early-stage and locally advanced non-small cell lung cancer. npj Precis. Onc. 9, 178 (2025). https://doi.org/10.1038/s41698-025-00984-9 Hashimoto T, Nakamura Y, Oki E, et al. Bridging horizons beyond CIRCULATE-Japan: a new paradigm in molecular residual disease detection via whole genome sequencing-based circulating tumor DNA assay. Int J Clin Oncol. 2024;29(5):495-511. doi:10.1007/s10147-024-02493-4 Bettegowda C, Sausen M, Lear y RJ, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med. 2014;6(224):224ra24. Rhoades J, Patel A, Xiong K, Blewett T, Li R, Walsh L, Crnjac A, Ratty JH, Limbo O, Hannigan A, Remland J, Brais L, Jain P, Sridhar S, Gilligan K, Carnes M, Shin KY, Catalano P, Wiener D, Papke DJ Jr, Ramesh A, Fu Y, Garces J, Mazloom A, Costa GL, Hu J, Makrigiorgos GM, Culver BP, Adalsteinsson VA, Enzinger P, Mamon H. Ultrasensitive circulating tumor DNA analysis improves detection of molecular residual disease in locally advanced esophageal cancer. Clin Cancer Res. 2026. In press. Dooley A, et al. Evaluation of whole-exome and whole-genome sequencing tumor-informed circulating tumor DNA MRD assays in patients with early triple-negative breast cancer (TNBC) receiving neoadjuvant chemotherapy (NAC) with or without olaparib: A prospective sub-study of the PARTNER trial. Poster presented at: American Society of Clinical Oncology (ASCO) Annual Meeting; May 29–June 2, 2026; Chicago, IL. J Clin Oncol. 2026;44(16_suppl):570. DOI:10.1200/JCO.2026.44.16_suppl.570. Hashimoto, T. et al. Validation of the ultrasensitive tumor-informed WGS MAESTRO MRD assay in β-CORRECT. Poster 4426P presented at ESMO 2026; October 23-27, 2026; Madrid, Spain. SOURCE Abbott